The difference between vaping CBD and ingesting CBD is the change in the bioavailability or rate at which it is absorbed into the body’s circulatory system. Unfortunately, CBD has a naturally low bioavailability since when CBD is ingested it needs to be processed by the digestive tract and liver before it enters the bloodstream. However, vaping CBD oil allows it to be dispersed immediately into your lungs and bloodstream. When CBD is vaped it reaches 50 to 60 percent bioavailability versus the 15 percent when taken orally. Vaping also dramatically decreases the amount of time it takes for CBD to enter the bloodstream, speeding up the onset of its benefits.